Open AccessThe effect of hyaluronic acid gel on preventing post-surgical adhesions after laparoscopic surgery
Author(s) -
Alp Yıldız
Publication year - 2018
Publication title -
international journal of scientific research and management
Language(s) - English
Resource type - Journals
ISSN - 2321-3418
DOI - 10.18535/ijsrm/v6i10.mp01
Subject(s) - hyaluronic acid , medicine , laparotomy , adhesion , surgery , laparoscopic surgery , infertility , retrospective cohort study , laparoscopy , population , pregnancy , chemistry , genetics , anatomy , environmental health , organic chemistry , biology
Intraperitoneal adhesions are an important cause of postoperative intestinal obstruction, abdominal discomfort, and infertility. Despite careful attention to minimize tissue trauma and ensure hemostasis, pelvic surgery is associated with both de novo adhesion formation and reformation. In this study our aim is to investigate the efficacy of hyaluronic acid gel on preventing/healing postoperative adhesions.
124 women on reproductive age who underwent emergency laparoscopic surgery (appendicitis, gynecologic emergencies, trauma, hernias ) included in this retrospective study. 28 of these patients underwent second-look surgery in 14-30 days. 17 of patients were applied hyaluronic acid gel on the initial surgery (Group-1) and 11 of patients were not appiled (Group-2).
There were no signicant differences between the two groups for age and weight. The operating time was similar in the two groups. At follow-up, a signicantly (p<0.01) lower rate of postsurgical adhesions was observed in Group-1 in comparison with Group-2. The median rate of adhesions was signicantly (p<0.05) lower in patients treated with hyaluronic acid in respect to the group who treated surgery alone.
This study showed that hyaluronic acid treatment after laparospopy/laparotomy is a significantly effective and very cost-effective option for prevention and treatment of postoperative adhesions. We believe it is very important of usage hyaluronic acid especially on reproductive age women population in order to prevent the worsening effect of postsurgical adhesion on fertility.