Open AccessExtensive vascular thrombosis in immunocompetent patients with acute cytomegalovirus infection: a case report of a peculiar phenomenon
Author(s) -
Gida Ayada,
Galit Levin,
Tamar Gottesman,
Shaul Lev
Publication year - 2020
Publication title -
international journal of medical science and clinical invention
Language(s) - English
Resource type - Journals
eISSN - 2454-9576
pISSN - 2348-991X
DOI - 10.18535/ijmsci/v7i11.02
Subject(s) - medicine , cytomegalovirus , thrombosis , asymptomatic , mononucleosis , cytomegalovirus infection , venous thrombosis , encephalitis , meningitis , immunology , surgery , herpesviridae , human cytomegalovirus , viral disease , virus
Background: acute Cytomegalovirus (CMV) infection in the immunocompetent usually asymptomatic or may present as a mononucleosis syndrome, but sometimes it is present as colitis, meningitis, encephalitis, or as ocular involvement and others. Thrombosis is considered an extremely rare manifestation described only in a scarce number of case reports.
Case presentation: a 30-years-old immunocompetent patient present with extensive vascular thrombosis shortly after a diagnosis of CMV infectious mononucleosis was established. Other than morbid obesity, no other risk factors existed. Therapeutic anticoagulation was associated with clinical improvement.
Conclusion: CMV infection can be associated with acute venous thrombosis in immunocompetent patients. An active search for both underlying prothrombotic conditions and other organ involvement sounds reasonable and should be treated, if found, accordingly.