Open AccessCombined Aortic and Mitral Valve Stenosis in Mucopolysaccharidosis Syndrome Type I-S: A Report of a Rare Case
Author(s) -
Hakimeh Sadeghian,
Afsaneh Sadeghian,
Bahareh Eslami,
Seyed Hesameddin Abbasi,
Masoumeh LotfiTokaldany
Publication year - 2021
Publication title -
the journal of tehran university heart center./the journal of tehran university heart center
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.182
H-Index - 13
eISSN - 2008-2371
pISSN - 1735-8620
DOI - 10.18502/jthc.v16i1.6598
Subject(s) - medicine , cardiology , stenosis , mucopolysaccharidosis , left ventricular hypertrophy , calcification , mitral valve , aortic valve stenosis , aortic valve , blood pressure
Mucopolysaccharidosis (MPS) syndrome is an inherited metabolic disorder. In more than half of the patients with MPS syndrome, heart valve involvement is reported; however, combined aortic and mitral valve stenosis in MPS syndrome type I-S is very rare. We describe a 39-year-old man with severe mitral and aortic valve stenosis due to MPS syndrome type I-S. Transthoracic and transesophageal echocardiography revealed severe thickening and calcification in the aortic and mitral valves with severe left ventricular hypertrophy. The coronary arteries were normal in angiography.