Open AccessEstimation of Serum and Seminal Plasma Levels of Glactin-1 in Non-Obstructive Azoospermia Cases and Their Correlations with the Rate of Sperm Retrieval: A Comparative Prospective Study
Author(s) -
Sameh Fayek GamalEl Din,
Khadiga Abougabal,
Hany Mohammed Saad,
Mohamed Shokr Mohamed,
Amira Mahmoud Mohamed Ali,
Ahmed Abo Sief
Publication year - 2022
Publication title -
journal of reproduction and infertility
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.495
H-Index - 22
eISSN - 2251-676X
pISSN - 2228-5482
DOI - 10.18502/jri.v23i4.10810
Subject(s) - azoospermia , receiver operating characteristic , obstructive azoospermia , biomarker , spermatogenesis , medicine , sperm , andrology , prospective cohort study , area under the curve , gastroenterology , urology , endocrinology , infertility , chemistry , biology , pregnancy , biochemistry , genetics
Remarkably, the current study is one of the first to deploy galectin-1 (Gal-1) in determining the degree of impairment of spermatogenesis among cases with non-obstructive azoospermia (NOA) as well as utilizing it as a biomarker to predict the rate of sperm retrieval in these patients. The purpose of the study was to evaluate the seminal plasma and serum levels of Gal-1 in NOA patients as well as their correlations with Johnsen's tubular biopsy scoring (JTBS).