Open AccessEstrogenic Effect of Scoparia dulcis (Linn) Extract in Mice Uterus and In Silico Molecular Docking Studies of Certain Compounds with Human Estrogen Receptors
Author(s) -
Khamhee Wangsa,
Indira Sarma,
Purbajyoti Saikia,
Dhanabalan Ananthakrishnan,
Hari Prasad Sarma,
D. Velmurugan
Publication year - 2020
Publication title -
journal of reproduction and infertility
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.495
H-Index - 22
eISSN - 2251-676X
pISSN - 2228-5482
DOI - 10.18502/jri.v21i4.4329
Subject(s) - estrogen receptor , chemistry , receptor , docking (animal) , estrogen , estrogen receptor alpha , pharmacology , endocrinology , medicine , biochemistry , biology , nursing , cancer , breast cancer
Scoparia dulcis Linn. is reported to be used by women of Assam and Arunachal Pradesh in northeast India for treating menstrual disorders. Scoparia dulcis contains compounds that bind with estrogen receptors (ERα and ERβ) evidenced by increased PCNA in endometrial epithelium.