Open AccessThe Role of Tranexamic Acid in Reducing Blood Loss Following Total Joint Arthroplasty: A Review Article
Author(s) -
Ehsan Fallah,
Alireza Moharrami,
Amir Hossein Ahmadi Nouri,
Mir Mansour Moazen Jamshidi,
Amir Reza Mafi,
Seyed Mohammad Javad Mortazavi
Publication year - 2022
Publication title -
journal of orthopedics and spine trauma
Language(s) - English
Resource type - Journals
eISSN - 2538-4600
pISSN - 2538-2330
DOI - 10.18502/jost.v8i1.9038
Subject(s) - tranexamic acid , medicine , blood loss , joint arthroplasty , surgery , arthroplasty , anesthesia
Total Joint Arthroplasty (TJA) is a major surgery performed for patients who suffer from severe joint destruction. It is so important to reduce the blood loss in the TJA surgery to decrease the infection rate, falling, and other complications following the surgery. Many methods could reduce blood loss, such as mechanical methods and chemical methods. Tranexamic acid (TXA) is a chemical method to reduce blood loss in surgery. There are numerous methods of administration of TXA in the literature, such as intravenous (IV), intra-articular, and combination of intra-articular and -venous methods. In the present review article, we review the studies that compared the efficacy of each method of the TXA administration.