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Relationship Between Shift Work and Lipid Profiles: A Prospective Cohort Study with Application of Ordinal Multilevel Modeling
Author(s) -
Amineh kousehlou,
Mohammad Gholami-Fesharaki
Publication year - 2020
Publication title -
journal of biostatistics and epidemiology
Language(s) - English
Resource type - Journals
eISSN - 2383-420X
pISSN - 2383-4196
DOI - 10.18502/jbe.v5i4.3871
Subject(s) - confounding , body mass index , medicine , prospective cohort study , demography , cohort , odds ratio , cohort study , multilevel model , shift work , confidence interval , gerontology , physical therapy , statistics , mathematics , psychiatry , sociology
A very limited evidences are available that considered the relationship between Shift Work (SW) and lipid variables. Objectives: As the importance of this subject, this prospectively cohort study examines the association between SW and Body Mass Index (BMI) and lipid profiles among male workers using multilevel ordinal model. Methods: This five years prospective cohort study has been conducted in random selected workers (using cluster sampling) who work in Esfahan’s Mobarakeh Steel Company (EMSC) (Iran) between 2011 and 2015. Results: The study sample included 1626 male workers (mean age=41.5). Among these subjects, 652 (40.01%), 183 (11.3%) and 791 (48.6%) were day workers, weekly rotating shift workers and routinely rotating. After controlling for several confounding variables, except HDL and Cholesterol, the odds ratio for high HDL was decreased by 26% (OR=0.74, P<0.001) and increased for TG by 36% in weekly rotating shift workers compared to day workers. Conclusion: Since weekly rotating shift workers had higher mean value of TG in their serum compared to day workers, they should limit eating high-fat diets in order to decrease risk of CVD.

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