Open AccessLncRNA HOTAIR Promotes Proliferation of Malignant Mela-noma Cells Through NF-κB Pathway
Author(s) -
Jun Wang,
Jingxin Chen,
Gang Jing,
Daoquan Dong
Publication year - 2020
Publication title -
iranian journal of public health
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.452
H-Index - 39
eISSN - 2251-6093
pISSN - 2251-6085
DOI - 10.18502/ijph.v49i10.4696
Subject(s) - hotair , noma , long non coding rna , cancer research , biology , downregulation and upregulation , computer science , genetics , gene , telecommunications , telecommunications link
To study the effects of long non-coding ribonucleic acid (lncRNA) HOX transcript antisense intergenic RNA (HOTAIR) on the proliferation and apoptosis of malignant melanoma cells, and to explore its specific regulatory mechanism through the nuclear factor-kappa B (NF-ϰB) signaling pathway.