Open AccessCloning and Expression of a New Trichinella spiralis Serine Protease and Its Role in Invading Host Intestinal Epithelium
Author(s) -
Fang Liu,
Yan Song,
Ru Zhang,
Ruo Dan Liu,
Peng Jiang,
Jing Cui,
Zhong Quan Wang
Publication year - 2022
Publication title -
iranian journal of parasitology./iranian journal of parasitology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.477
H-Index - 27
eISSN - 2008-238X
pISSN - 1735-7020
DOI - 10.18502/ijpa.v17i3.10628
Subject(s) - trichinella spiralis , biology , intestinal epithelium , epithelium , microbiology and biotechnology , serine protease , immunofluorescence , antibody , immunology , protease , helminths , biochemistry , genetics , enzyme
In previous studies, a new Trichinella spiralis serine protease 1.1 (TsSP1.1) was identified in surface proteins of T. spiralis muscle larvae (ML) by proteomics analysis, but its functions in T. spiralis infection are unknown. The aim of this study was to investigate the roles of TsSP1.1 during larval intrusion of gut epithelium.