Open AccessAssessment of influenza A (H1N1, H3N2) oseltamivir resistance during 2017-2019 in Iran
Author(s) -
Amytis Gholami,
Nazanin Zahra ShafieiJandaghi,
Nastaran Ghavami,
Forough Tavakoli,
Jila Yavarian,
Talat MokhtariAzad
Publication year - 2022
Publication title -
iranian journal of microbiology.
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.37
H-Index - 27
eISSN - 2008-4447
pISSN - 2008-3289
DOI - 10.18502/ijm.v14i4.10241
Subject(s) - oseltamivir , neuraminidase , virology , biology , neuraminidase inhibitor , drug resistance , virus , h5n1 genetic structure , gene , pandemic , antigenic drift , influenza a virus , antigenic shift , microbiology and biotechnology , medicine , covid-19 , genetics , infectious disease (medical specialty) , disease , pathology
Neuraminidase inhibitors (NAIs) as an imperative antiviral for influenza prophylaxis and treatment are being consumed worldwide. Increasing use of these antivirals might be associated with drug resistance. Regarding the significance of these variations, this study aimed to investigate the mutations occurring in the NA gene of influenza A viruses leading to oseltamivir resistance during 2017-2019 in Iran.