Open AccessExpression analysis of miRNA-155 level in Helicobacter pylori related inflammation and chronic gastritis
Author(s) -
Ramina Mahboobi,
Fatemeh Fallah,
Abbas Yadegar,
Naghi Dara,
Maryam Kazemi Aghdam,
Behnoush Asgari,
Mojdeh Hakemi-Vala
Publication year - 2022
Publication title -
iranian journal of microbiology.
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.37
H-Index - 27
eISSN - 2008-4447
pISSN - 2008-3289
DOI - 10.18502/ijm.v14i4.10235
Subject(s) - gastritis , helicobacter pylori , chronic gastritis , gastroenterology , medicine , microrna , caga , genotyping , helicobacter , inflammation , biology , immunology , gene , genotype , biochemistry , virulence
Helicobacter pylori , is a major etiologic agent associated with gastritis. There is more evidence of noncoding microRNAs (miRs) dysregulation in gastrointestinal diseases, including inflammation caused by Helicobacter pylori. Also, the classification of gastrointestinal malignancies using the miRs profile is better than the protein profile. MiRNA-155( miRNA-155 ) among other miRs plays an important role in control of inflammation and gastric malignancy, so it can be remarkable prognosis marker of gastric cancer in the phase of chronic gastritis. The aim of this study was to compare the expression of miRNA-155 in gastric biopsy and serum samples of adult patients with chronic gastritis.