Open AccessRelapse of Sulfasalazine-induced DRESS Syndrome Following the Administration of Contrast Media: A Case Report
Author(s) -
Niayesh Mohebbi,
Hamidreza TaghvayeMasoumi,
Malihe Khosravi-Khezri,
Mona Talaschian
Publication year - 2021
Publication title -
case reports in clinical practice
Language(s) - English
Resource type - Journals
eISSN - 2538-2691
pISSN - 2538-2683
DOI - 10.18502/crcp.v6i3.7121
Subject(s) - sulfasalazine , medicine , exacerbation , hypersensitivity reaction , sulfonamide , dermatology , antibiotics , eosinophilia , iodinated contrast media , disease , chemistry , ulcerative colitis , stereochemistry , microbiology and biotechnology , biology
Sulfasalazine, a non-antibiotic sulfonamide, is associated with severe hypersensitivity reactions, including Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) syndrome. We report a case of sulfasalazine-induced DRESS syndrome that relapsed following the administration of visipaque® (iodixanol). Macular rashes, pruritus, and an acute exacerbation of dyspnea were immediately observed after the administration of contrast media. It seems that patients suffering from DRESS syndrome are sensitive to the administration of other new medications with a high possibility of hypersensitive reactions. It can be concluded that iodinated contrast media should be used cautiously in patients with DRESS syndrome.