Open AccessPeriductal Stromal Sarcoma of the Breast: A Case Report
Author(s) -
Elham Nazar,
Zohre Shabanzadeh
Publication year - 2021
Publication title -
case reports in clinical practice
Language(s) - English
Resource type - Journals
eISSN - 2538-2691
pISSN - 2538-2683
DOI - 10.18502/crcp.v6i2.6680
Subject(s) - medicine , phyllodes tumor , breast cancer , sarcoma , modified radical mastectomy , radiation therapy , presentation (obstetrics) , stromal cell , mastectomy , immunohistochemistry , adjuvant radiotherapy , wide local excision , stroma , stromal tumor , case presentation , epithelioid sarcoma , pathology , radiology , cancer , surgery
Periductal Stromal Sarcoma (PSS), especially spindle and epithelioid types, is a rare subtype of the malignant fibroepithelial tumor with benign ductal elements and a sarcomatous stroma composed of spindle cells. The therapeutic management of PSS is based on wide surgery with free margins, and adjuvant therapies are not required.
Case Presentation: This report describes a 37-year-old woman who presented to Shariati hospital with a right breast mass for review and a second opinion pathology report. The patient had undergone a radical mastectomy in another hospital three months previously. Histological and immunohistochemical examinations revealed PSS and all dissected lymph nodes were free of tumor. Based on the diagnosis, the patient received no adjuvant treatment (such as chemotherapy or radiotherapy). After nine months of close follow-up examinations, no recurrence was observed.
Conclusion: PSS is an extremely rare disease with low-grade sarcomatous behavior, which may evolve into a phyllodes tumor or an entity of breast cancer. Therefore, frequent follow-up examinations are required.