Open AccessAcute pulmonary histoplasmosis related to occupational roofing: A case report of two brothers
Author(s) -
Martin Gi,
Timothy McCann,
Adrián Riva-Moscoso,
Fortunato S. Príncipe-Meneses,
Diego ChambergoMichilot
Publication year - 2022
Publication title -
current medical mycology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.369
H-Index - 6
eISSN - 2423-3439
pISSN - 2423-3420
DOI - 10.18502/cmm.7.4.8409
Subject(s) - histoplasmosis , asymptomatic , medicine , histoplasma , occupational lung disease , histoplasma capsulatum , carriage , dermatology , pediatrics , lung , surgery , pathology
Background and Purpose: Histoplasma capsulatum is the cause of a prevalent fungal disease in certain regions in the United States of America, like Ohio and the Mississippi River. Its clinical manifestations range from asymptomatic to life-threatening diseases,according to the immune system. A definitive diagnosis is made by biopsy.
Case report: Two middle-aged brothers presented with a nine-day history of severe progressive dyspnea. Both were living in Cincinnati, Ohio, and encountered bird droppings 7 days prior to symptoms while working on a roofing project. It should be mentioned that they were not wearing masks. After extensive testing, they were diagnosed with acute pulmonary histoplasmosis. Both were successfully treated with azole-derivative fungal therapy.
Conclusion: This is the first case of histoplasmosis acquired through occupational exposure related to roofing and is unique given the two patients were siblings.