Open AccessHigh prevalence of asymptomatic nosocomial candiduria due to Candida glabrata among hospitalized patients with heart failure: a matter of some concern?
Author(s) -
Seyed Reza Âghili,
Mahdi Abastabar,
Aria Soleimani,
Iman Haghani,
Soheil Azizi
Publication year - 2021
Publication title -
current medical mycology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.369
H-Index - 6
eISSN - 2423-3439
pISSN - 2423-3420
DOI - 10.18502/cmm.6.4.5327
Subject(s) - voriconazole , fluconazole , candida glabrata , asymptomatic , amphotericin b , caspofungin , medicine , itraconazole , heart failure , incidence (geometry) , candida albicans , urinary system , microbiology and biotechnology , antifungal , biology , dermatology , physics , optics
Heart failure is a leading cause of hospitalization, and asymptomatic candiduria is common in hospitalized patients with low morbidity. However, in most patients, it is resolved spontaneously on the removal of the catheter. Despite the publication of guidelines, there are still controversies over the diagnosis and management of candiduria. However, in hospitalized patients with heart failure, the decision to treat candiduria is especially important since the nosocomial infections are associated with an increase in morbidity, mortality, length of hospital stay, and healthcare costs. Some species of Candida , such as Candida glabrata , are increasingly resistant to the first-line and second-line antifungal medications. The present study aimed to investigate the incidence of asymptomatic Candida urinary tract infection due to C. glabrata and antifungal susceptibility of Candida isolates in hospitalized patients with heart failure.