Open AccessAntifungal susceptibility pattern and biofilm-related genes expression in planktonic and biofilm cells of Candida parapsilosis species complex
Author(s) -
Mona Modiri,
Seyed Jamal Hashemi,
Roshanak Daie Ghazvini,
Sadegh Khodavaisy,
Ali Ahmadi,
Mansoureh Ghaffari,
Sassan Rezaie
Publication year - 2019
Publication title -
current medical mycology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.369
H-Index - 6
eISSN - 2423-3439
pISSN - 2423-3420
DOI - 10.18502/cmm.5.4.1950
Subject(s) - biofilm , candida parapsilosis , microbiology and biotechnology , antifungal , biology , gene , bacteria , genetics
Candida parapsilosis complex isolates are mainly responsible for nosocomial catheter-related infection in immunocompromised patients. Biofilm formation is regarded as one of the most pertinent key virulence factors in the development of these emerging infections. The present study aimed to compare in vitro antifungal susceptibility patterns and biofilm-related genes expression ratio in planktonic and biofilm's cells of clinically C. parapsilosis complex isolates.