Open AccessLivedo reticularis following drug interaction of sertraline and amantadine in a patient with obsessive-compulsive disorder and depression: A brief report
Author(s) -
Somayeh Panahi,
Fatemeh Mohamadian Rasnani,
Fatemeh Zare,
Reza Bidaki,
Mohadeseh Asadi
Publication year - 2022
Publication title -
advances in pharmacology and therapeutics journal
Language(s) - English
Resource type - Journals
ISSN - 2783-3445
DOI - 10.18502/aptj.v1i2.8672
Subject(s) - amantadine , livedo reticularis , medicine , parkinsonism , sertraline , resting tremor , postural tremor , dermatology , psychology , psychiatry , pharmacology , essential tremor , antidepressant , disease , anxiety
Livedo reticularis (LR) is a cutaneous vascular pattern that presents with reticular patch morphology. LR is a manifestation of a wide range of diseases, from idiopathic to systemic. We reported the clinical image of a patient with obsessive-compulsive disorder (OCD) and LR associated with amantadine use. On examination, mild postural tremor was left-handed and had a kinetic tremor. Rest tremor and re-emerge tremor were detected in addition to mild rigidity and bradykinesia in the patient; we proposed probable drug-induced Parkinsonism.
We should notice skin lesions after amantadine use and consider LR after the prescription of it. Also, co-administration of SSRIs and amantadine may increasethe probability of LR.