Open AccessKawasaki Disease Triggered by Epstein-Barr Virus Infection: A Case Report
Author(s) -
Houman Hashemian,
Yasaman Ashjari,
Esfandiar Nazari
Publication year - 2021
Publication title -
acta medica iranica.
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.218
H-Index - 27
eISSN - 1735-9694
pISSN - 0044-6025
DOI - 10.18502/acta.v59i12.8069
Subject(s) - medicine , kawasaki disease , leukocytosis , vasculitis , disease , virus , coronary arteries , infectious disease (medical specialty) , coronary artery aneurysm , complication , systemic vasculitis , immunology , epstein–barr virus infection , epstein–barr virus , cardiology , artery
Kawasaki disease (KD) is the most common cause of acquired heart disease today. An important and enduring complication of KD is a coronary aneurysm, whose early diagnosis and treatment can reduce the risk from 25% to 3%. Diagnosis of this disease is mainly clinical, although leukocytosis, increased erythrocyte sedimentation rate, and echocardiography are helpful in diagnosis. The cause of KD remains unknown, but the most common hypothesis is an abnormal immune response that is likely caused by an infectious agent, possibly in a favorable genetic background, and leads to vasculitis of the middle arteries, especially coronary arteries of the heart. Numerous infectious agents have been suggested in this regard. Co-infection with KD can also delay diagnosis. In this article, we introduce five years and seven months child who developed Kawasaki disease within a few days of the onset of Epstein-Barr virus infection.