Open AccessA Rare Case Report of Postmenopausal Virilization: Ovarian Steroid Cell Tumor
Author(s) -
Mahbube Ebrahimpur,
Mohammad Reza Mohajeri-Tehrani,
Hana Saffar,
Mahnaz Pejman Sani
Publication year - 2020
Publication title -
acta medica iranica.
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.218
H-Index - 27
eISSN - 1735-9694
pISSN - 0044-6025
DOI - 10.18502/acta.v57i12.3471
Subject(s) - virilization , medicine , hyperandrogenism , ovary , ovarian tumor , hysterectomy , testosterone (patch) , gynecology , pathology , androgen , ovarian cancer , hormone , cancer , polycystic ovary , insulin resistance , obesity
Ovarian steroid cell tumors are rare, life-threatening neoplasms that make about 0.1% of all primary ovarian tumors. They frequently present in premenopausal women with the manifestation of virilization. We report a 58-year-old postmenopausal woman that referred to our clinic with clinical manifestation of virilization. Laboratory findings showed markedly elevated serum testosterone level and ultrasound showed 2 follicles with 7 mm diameters in the left ovary. She treated by bilateral salpingo-oophorectomy and synchronous hysterectomy. Histological pathology confirmed a benign steroid cell tumor. The presentation of new-onset and rapid progressive hyperandrogenism is rare in postmenopausal women. In diagnosis, we must consider adrenal and ovarian malignancies. Stromal luteoma is a rare benign ovarian tumor, Which is treated with surgical treatment.