Open AccessInvestigation of Impact of Trinitroglycerin Conjugated Cardioplegia on Myocardial Protection of Patients With Coronary Artery Bypass Grafting
Author(s) -
Mohammad Hassan Nemati,
Hasan Badie,
Mansour Jannati
Publication year - 2020
Publication title -
acta medica iranica.
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.218
H-Index - 27
eISSN - 1735-9694
pISSN - 0044-6025
DOI - 10.18502/acta.v57i10.3246
Subject(s) - medicine , bypass grafting , inotrope , artery , cardiology , ischemia , myocardial ischemia , grafting , anesthesia , chemistry , organic chemistry , polymer
Pharmacologic-conjugated-cardioplegia is one of the strategies against ischemia and reperfusion. The aim of this study was to investigate the impact of nitroglycerin on myocardial protection and postoperative outcomes. This was a case-control study performed on 91 patients undergoing coronary artery bypass grafting in Faghihi Hospital, Shiraz University of Medical Sciences. Patients were randomly divided into case and control groups. Trinitroglycerin Conjugated Cardioplegia on Myocardial Protection of Patients with Coronary Artery Bypass Grafting. As a result of nitroglycerin, the number of patients requiring inotrope administration was increased. No other significant alteration was observed between two groups in neither of ischemic features nor postoperative outcomes. In conclusion, nitroglycerin conjugated cardioplegia, with the condition of this study, demonstrated a negative inotrope requirement without improvement in myocardium protection. © 2019 Tehran University of Medical Sciences. All rights reserved.