Open AccessUsing of the method of electron microscopy for the identification and analysis of clinically implicit pathogenetic manifestations
Author(s) -
L. G. Nikonova,
В. В. Банин,
И. Г. Стельникова
Publication year - 2018
Publication title -
žurnal anatomii i gistopatologii
Language(s) - English
Resource type - Journals
ISSN - 2225-7357
DOI - 10.18499/2225-7357-2018-7-3-113-116
Subject(s) - golgi apparatus , endoplasmic reticulum , vacuole , ultrastructure , cytoplasm , pancreas , secretion , electron microscope , islet , diabetes mellitus , endocrinology , microbiology and biotechnology , hormone , pathology , biology , medicine , chemistry , physics , optics
Electron microscopic examination of B cells of pancreatic islets of the pancreas in dogs with normal (n=10) and impaired glucose tolerance (n=10) was performed. Ultrastructural features of the organization of insulin cells associated with an increased requirement of the hormone in the body with the latent form of diabetes mellitus are established. In B cells, signs of functional tension due to unregulated secretion, manifested by the expansion of endoplasmic reticulum cisterns, Golgi complex hypertrophy, an increase in the number of immature secretory granules and vacuoles in the cytoplasm are revealed in B cells.