Open AccessImmunotherapy at the diabetes 2 types, complicated by the syndrome of diabetic foot, by the complex of natural cytokines and antimicrobial peptides
Author(s) -
Л. В. Ковальчук,
Vladimir Vasilievich Potemkin,
Tatiaikolaevna Baldina,
Pavel Borisovich Barbin
Publication year - 2011
Publication title -
vestnik èksperimentalʹnoj i kliničeskoj hirurgii
Language(s) - English
Resource type - Journals
eISSN - 2409-143X
pISSN - 2070-478X
DOI - 10.18499/2070-478x-2011-4-1-85-89
Subject(s) - medicine , antimicrobial , diabetic foot , antioxidant , diabetes mellitus , immunotherapy , immune system , lipid peroxidation , antibody , immunology , gastroenterology , endocrinology , oxidative stress , microbiology and biotechnology , biochemistry , biology
In research results of inspection and treatment of 75 patients with DFS are analysed. Patients are divided into 2 investigated groups depending on character of disease and treatment schemes. The first group have made 25 (33,3 %) patients by whom treatment under the traditional scheme (antibacterial therapy, disaggregants, angioprotectors, antioxidants, correction level of hyperglycemia, surgical treatment, bandagings with ointment of Levomekol was spent). In the second group are included 50 (66,7 %) patients with purulent-necrotic defeats of foot, in which treatment, along with the standard methods, it was used immunecorrection by a preparation "Superlimf". The control group of 25 persons is presented by healthy people. It is established that application immunotherapy by complex natural cytokines and antimicrobial peptides at a diabetes 2 types, complicated by the diabetic foot syndrome, pathogenetic is proved. Оbserved decrease of activity of processes lipid peroxidation was, stabilization in antioxidant blood protection, decrease endogenous intoxication, normalisation of phagocytic a component of immune system, level of circulating immunoglobulin in blood. At patients about a syndrome of diabetic foot immunecorrection a preparation "Superlimf" is a choice method immunomodelling therapies