Open AccessANTIBIOTIC PROPHYLAXIS OF INFECTIVE ENDOCARDITIS IN DENTISTRY
Author(s) -
Э. В. Гайсина,
Elena Gaysina,
Т. М. Еловикова,
Tat'yana Elovicova,
Н. В. Изможерова,
Н. В. Изможерова,
Софья Мотоусова,
Sof'ya Motousova
Publication year - 2019
Publication title -
problemy stomatologii
Language(s) - English
Resource type - Journals
eISSN - 2412-9461
pISSN - 2077-7566
DOI - 10.18481/2077-7566-2019-15-2-4-10
Subject(s) - infective endocarditis , medicine , antibiotic prophylaxis , endocarditis , bacteremia , intensive care medicine , amoxicillin , antibiotics , heart disease , cochrane library , surgery , randomized controlled trial , microbiology and biotechnology , biology
Background. Infective endocarditis is a serious disease and has the risk of disability and high mortality. This disease can be a terrible complication of both general surgical and dental invasive procedures. The problem of infective endocarditis is relevant in most countries of the world, which determine the need for targeted prevention of dental interventions. The most important pathogenetic component of this disease is transient bacteremia, which develops when the skin and mucous membrane of the oral cavity are damaged under the influence of various traumatic agents. Antibiotic prophylaxis prevents of infective endocarditis and helps to reduce the risk.
Objectives ― to identify and analyze the most effective methods of antibiotic prophylaxis of IE at the dental admission.
Methodology. A review of literature - publications of domestic and foreign studies using the scientific search library databases PubMed, Medline, Cochrane, Elibrary. Total found 38 publications from Russia, USA, Germany, Jordan, Saudi Arabia, Singapore, Japan and other countries.
Results. The review examines studies - questioning people, clinical studies with "double glare", publication of patents, revealing the attitude to antibiotic prophylaxis of infective endocarditis at a dental reception in the world, and also analyzed the choice of drugs and their use.
Conclusions. The most preferred option is to carry out antibiotic prophylaxis of the disease in people with a high risk factor, which include patients with prosthetic heart valves, congenital heart defects and patients with a history of infectious endocarditis. The drug of choice among antibacterial agents is the use of amoxicillin / clavulanic acid combination.