Open AccessPredictive value of the N-terminal prohormone of brain natriuretic peptide in the long-term prognosis of ventricular arrhythmia in diabetic patients with acute coronary syndrome of young and middle age
Author(s) -
Zheming Wang,
Elena A. Asafieva,
Т И Макеева
Publication year - 2020
Publication title -
aktualʹnye problemy mediciny
Language(s) - English
Resource type - Journals
ISSN - 2687-0940
DOI - 10.18413/2687-0940-2020-43-4-522-538
Subject(s) - medicine , cardiology , conventional pci , acute coronary syndrome , percutaneous coronary intervention , myocardial infarction , diabetes mellitus , population , brain natriuretic peptide , heart failure , endocrinology , environmental health
The article investigates the prognostic value of pro-B-type N-terminal natriuretic peptide (NTproBNP) in connection with ventricular extrasystoles (VES) in a population of patients with diabetes mellitus with acute coronary syndrome (ACS) after successful coronary reperfusion by percutaneous coronary intervention (PCI). Patients with ACS were examined by defining biomarkers and performing echocardiography (EchoCG) on the first day of ACS after PCI with stenting of the infarction-related coronary artery, and Holter monitoring of electrocardiography (HM-ECG) on the second day after PCI; 12 months later, EchoCG, HM-ECG and NT-proBNP determination were repeated. It was found that the incidence of VES in the long-term prognosis among ACS patients with diabetes of young and middle age was more frequent than in patients without diabetes. A positive correlation was found between the NTproBNP level and ventricular arrhythmia in ACS patients with diabetes mellitus. It has been proven that a high level of NT-proBNP on the first day in patients with ACS after PCI as an independent indicator of risk to development of VES in long-term prognosis.