Open AccessStructure of the arginase coding gene and its transcript in Aspergillus nidulans.
Author(s) -
Piotr Borsuk,
Agnieszka Dzikowska,
Joanna Empel,
Anna Grzelak,
Rafał Grześkowiak,
Piotr Węgleński
Publication year - 1999
Publication title -
acta biochimica polonica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.452
H-Index - 78
eISSN - 1734-154X
pISSN - 0001-527X
DOI - 10.18388/abp.1999_4172
Subject(s) - aspergillus nidulans , arginase , gene , biology , untranslated region , gene expression , messenger rna , transcription (linguistics) , regulation of gene expression , genetics , arginine , amino acid , linguistics , philosophy , mutant
The arginase structural gene (agaA) from Aspergillus nidulans has been cloned and characterised. Depending on the growth conditions of the mycelium, transcripts of this gene have different 5'ends. These differences could result either from the presence of multiple transcription initiation sites or from differential processing of mRNA. The agaA mRNA has a long 5'UTR with a potentially complex secondary structure. Putative arginine binding aptamers were found in this UTR suggesting interesting possibilities for regulation of the agaA expression.