Protection of cattle against bovine leukemia virus (BLV) infection could be attained by DNA vaccination. | Zendy

Anna BrillowskaDąbrowska | Zendy; Sławomir Dąbrowski | Zendy; J. Rułka | Zendy; P. Kubis | Zendy; E. Buzała | Zendy; Józef Kur | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Protection of cattle against bovine leukemia virus (BLV) infection could be attained by DNA vaccination.

Author(s) -

Anna BrillowskaDąbrowska,

Sławomir Dąbrowski,

J. Rułka,

P. Kubis,

E. Buzała,

Józef Kur

Publication year - 1999

Publication title -

acta biochimica polonica

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.452

H-Index - 78

eISSN - 1734-154X

pISSN - 0001-527X

DOI - 10.18388/abp.1999_4121

Subject(s) - bovine leukemia virus , virology , biology , dna vaccination , plasmid , immune system , virus , glycoprotein , vector (molecular biology) , gene , antibody , vaccination , recombinant dna , microbiology and biotechnology , immunology , genetics

The bovine leukemia virus (BLV) envelope gene encoding extracellular glycoprotein gp51 and transmembrane glycoprotein gp30 was cloned into a vehicle expression vector under the human cytomegalovirus (CMV) intermediate early promoter. The intramuscular injection of this plasmid vector generated a cellular immune response. Seven out of ten cows vaccinated with the DNA construct resisted a drastic challenge (500 BLV-infected lymphocytes as an infectious dose).

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research