Translational frameshift sites within bacteriophage lambda genes rexA and cI. | Zendy

Sidney Hayes | Zendy; Harold J Bull | Zendy

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Translational frameshift sites within bacteriophage lambda genes rexA and cI.

Author(s) -

Sidney Hayes,

Harold J Bull

Publication year - 1999

Publication title -

acta biochimica polonica

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.452

H-Index - 78

eISSN - 1734-154X

pISSN - 0001-527X

DOI - 10.18388/abp.1999_4109

Subject(s) - frameshift mutation , operon , repressor , bacteriophage , lambda , genetics , mechanism (biology) , lambda phage , polarity (international relations) , gene , biology , physics , mutation , escherichia coli , gene expression , quantum mechanics , cell

Phage lambda's cI-rexA-rexB operon displays an intriguing example of regulation by an unexplained mechanism of polarity. We have identified three potential -1 translational frameshift sites and present a model for translational frameshift suppression by lambda's CI repressor as a mechanism of regulating operon polarity, implying an additional role for CI self-regulation.

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