Implication of glycolipids in lens fiber development. | Zendy

M Ogiso | Zendy

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Implication of glycolipids in lens fiber development.

Author(s) -

M Ogiso

Publication year - 1998

Publication title -

acta biochimica polonica

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.452

H-Index - 78

eISSN - 1734-154X

pISSN - 0001-527X

DOI - 10.18388/abp.1998_4243

Subject(s) - lens (geology) , lens fiber , epitope , glycolipid , chemistry , nucleus , microbiology and biotechnology , biology , biochemistry , antigen , immunology , paleontology

Mammalian lens contains Lewis(x), sialyl-Lewis(x) and alpha-galactosyl epitopes in neolactoseries glycosphingolipids. The expression of these three epitopes is not observed in lens epithelial cells, but is immunohistochemically detected in the inner cortical fibers and the lens nucleus. In embryonic chick lens, sialyl-Lewis(x)-containing gangliosides were also detected in the transitional zone and elongating lens fibers. Thus, the Lewis(x), sialyl-Lewis(x) and alpha- galactosyl epitopes may be associated with the differentiation and maturation of lens epithelial cells to lens fibers.

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