Open AccessActivity of cancer procoagulant (CP) in serum of patients with cancer of lung, breast, oesophagus and colorectum.
Author(s) -
Monika Rucińska,
M Furman,
Z Skrzydlewski,
E. H. Zaremba
Publication year - 1997
Publication title -
acta biochimica polonica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.452
H-Index - 78
eISSN - 1734-154X
pISSN - 0001-527X
DOI - 10.18388/abp.1997_4446
Subject(s) - medicine , lung cancer , breast cancer , colorectal cancer , cancer , lung , gastroenterology , stage (stratigraphy) , oncology , biology , paleontology
Activity of cancer procoagulant (CP) was studied in blood serum of 90 patients with cancer of lung, breast, oesophagus and colorectum, and of 15 healthy people. The activity of CP was determined by the coagulation method. Sera of patients with cancer showed higher mean activity of CP than sera of healthy control. Of the 90 cancer patients 78 were identified correctly by this test as having cancer (sensitivity 85%). In the case of lung and colorectal cancers the higher CP activity was observed the more advanced was the clinical stage of cancer, and the test was positive in 100%. After radical removal of malignant tumor of lung, decreased CP activity was found.