Open AccessModified substrates of DNA polymerases and design of antivirals.
Author(s) -
Alexander A. Krayevsky,
L. А. Alexandrova,
Natalia Dyatkina,
Marina K. Kukhanova,
Elena A. Shirokova
Publication year - 1996
Publication title -
acta biochimica polonica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.452
H-Index - 78
eISSN - 1734-154X
pISSN - 0001-527X
DOI - 10.18388/abp.1996_4523
Subject(s) - dna polymerase , polymerase , dna , nucleotide , chemistry , computational biology , biology , biochemistry , gene
The results obtained in our laboratory on investigating of substrate properties of a large number of compounds towards different DNA polymerases have been summarized. On the basis of systematic analysis a directed synthesis of nucleotides with antiviral properties was performed.