Open AccessSome recent trends and progress in nucleoside synthesis.
Author(s) -
Helmut Vorbrüggen
Publication year - 1996
Publication title -
acta biochimica polonica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.452
H-Index - 78
eISSN - 1734-154X
pISSN - 0001-527X
DOI - 10.18388/abp.1996_4514
Subject(s) - pyrimidine , purine , trimethylsilyl , nucleoside , chemistry , lewis acids and bases , trifluoromethanesulfonate , trimethylsilyl trifluoromethanesulfonate , nucleic acid , organic chemistry , nucleotide , combinatorial chemistry , stereochemistry , biochemistry , catalysis , gene , enzyme
Some recent progress concerning the optimal combinations of Lewis acids and solvents for the synthesis of pyrimidine as well as purine nucleosides is reviewed. Furthermore, the novel condensation of persilylated free sugars and heterocyclic bases in the presence of trimethylsilyl triflate to the corresponding persilylated nucleosides is discussed.