Open AccessRadiation induced oxidative DNA base damage and its repair in liver chromatin DNA of rats upon whole body gamma-irradiation.
Author(s) -
Tomasz H. Zastawny,
Beata Czerwińska,
Barbara Drzewiecka,
Ryszard Oliński
Publication year - 1996
Publication title -
acta biochimica polonica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.452
H-Index - 78
eISSN - 1734-154X
pISSN - 0001-527X
DOI - 10.18388/abp.1996_4494
Subject(s) - chromatin , dna , irradiation , chemistry , dna damage , oxidative damage , gamma irradiation , oxidative phosphorylation , biophysics , microbiology and biotechnology , biochemistry , oxidative stress , biology , physics , nuclear physics
The amount of all bases, except for 5,6-dihydroxyuracil were significantly increased in rat DNA upon cobalt-60 gamma-irradiation. Control values were recovered 12 h after irradiation. The extent of DNA damage and repair was different for particular bases.