Open AccessThe intracellular serpin family.
Author(s) -
Renata Korpula-Mastalerz,
Adam Dubin
Publication year - 1996
Publication title -
acta biochimica polonica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.452
H-Index - 78
eISSN - 1734-154X
pISSN - 0001-527X
DOI - 10.18388/abp.1996_4474
Subject(s) - serpin , subfamily , intracellular , ovalbumin , biology , serine proteinase inhibitors , microbiology and biotechnology , biochemistry , genetics , protease , serine protease , enzyme , gene , immune system
The serpins are widely distributed, structurally related family of proteins with diverse functions. Most of the known serpins are proteinase inhibitors, the majority being found as secreted species, however, there are a few that occur intracellularly and their physiological role remains unknown. Most of the intracellularly occurring serpins have been classified into the ovalbumin subfamily. The possible phytogenetic tree of 14 intracellular serpins is presented.