Open AccessActivity of aminoacyl-tRNA synthetases in experimental hyperthyroidism in muscle tissues of the rabbit.
Author(s) -
Kazimierz Pasternak,
S Szymonik-Lesiuk,
H Brzuszkiewicz-Zarnowska,
Tomasz Borkowski
Publication year - 1994
Publication title -
acta biochimica polonica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.452
H-Index - 78
eISSN - 1734-154X
pISSN - 0001-527X
DOI - 10.18388/abp.1994_4771
Subject(s) - amino acid , leucine , aminoacyl trna synthetase , tyrosine , isoleucine , transfer rna , biochemistry , serine , amino acyl trna synthetases , histidine , chemistry , biology , enzyme , rna , gene
In cardial and femoral muscles of rabbits specific activities of aminoacyl-tRNA synthetases for twenty amino acids were generally similar, namely the activities towards amino acids and their amides, leucine, isoleucine, histidine, tyrosine, proline and serine were considerably lower than towards the remaining amino acids. Specific activities of most aminoacyl-tRNA synthetases were higher in hyperthyroidism than in euthyreosis, and were higher in femoral muscle than in heart. The response to thyroxine treatment of individual aminoacyl-tRNA synthetases in both kinds of muscles varied with respect to most of the amino acids.