Open AccessThe content of N-acetylneuraminic acid in glycoproteins of erythrocyte membranes in Morris hepatoma 5123 bearing rats.
Author(s) -
Jolanta Batko,
H Karoń
Publication year - 1994
Publication title -
acta biochimica polonica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.452
H-Index - 78
eISSN - 1734-154X
pISSN - 0001-527X
DOI - 10.18388/abp.1994_4768
Subject(s) - fucose , galactose , membrane , chemistry , mannose , n acetylneuraminic acid , erythrocyte membrane , biochemistry , medicine , endocrinology , sialic acid , andrology , biology
Changes in the content of N-acetylneuraminic acid in rat erythrocyte membranes at different stages of experimental tumour (Morris hepatoma 5123) development were examined. Its content was lowered on the 30th and 40th day after transplantation of the tumour cells, as compared to the results for normal healthy rats. As a result of the tumour growth, the content of N-acetylgalactosamine, galactose and mannose in rat erythrocyte membranes became lowered, whereas that of glucose remained unchanged. The content of fucose was raised at early stage of tumour growth, and remained at this high level till the 40th day of experiment.