Open AccessOral Nutritional Supplementation for the Dietary Management of Malnutrition in Chronic Pulmonary Diseases: Study Protocol of a Randomized, Open-label, Multicentre Clinical Trial
Author(s) -
Edit Nádasi,
Gellért Cseh
Publication year - 2018
Publication title -
journal of nutritional biology
Language(s) - English
Resource type - Journals
ISSN - 2469-4142
DOI - 10.18314/jnb.v4i2.1324
Subject(s) - malnutrition , medicine , clinical trial , randomized controlled trial , intensive care medicine , population , disease , nutritional supplementation , environmental health
Disease-related malnutrition is frequent in patients with chronic pulmonary diseases. Though there is no doubt about the usefulness of Oral Nutritional Supplements (ONS) in managing malnutrition in such patients, only a handful of publications are available in the literature on clinical trials with ONS in this patient population. Since the digestion of macronutrients results in a strain on the respiratory functions in severe pulmonary diseases, the source of energy may also play a crucial role in the efficacy of nutrition with ONS in such patients. Here we present the study protocol of a randomized, open-label, multicentre clinical trial aimed to determine whether a new, condition-specific ONS (with a composition tailored to the needs of patients with decreased pulmonary functions) is more effective compared to a general ONS in improving the nutritional status in patients with compromised respiratory functions.