Open AccessOral Leukoplakia
Author(s) -
Tsvetan Borisov Tsvetanov
Publication year - 2017
Publication title -
international journal of medical and dental sciences
Language(s) - English
Resource type - Journals
eISSN - 2454-8952
pISSN - 2320-1118
DOI - 10.18311/ijmds/2017/18806
Subject(s) - medicine , leukoplakia , oral leukoplakia , lesion , malignant transformation , etiology , oral mucosa , biopsy , dermatology , pathology , cancer
Oral leukoplakia is defined as a predominantly white lesion of the oral mucosa that cannot be characterized as any other definable lesion; however, the lesion must be confirmed histopathologically by biopsy in order to discuss malignant transformation of oral leukoplakia. Malignant transformation rates of oral leukoplakia range from 0.13 to 17.5%, while the rates of five-year cumulative malignant transformation range from 1.2 to 14.5%. In this review were described some datas about the frequency, etiology and pathogenesis of oral leukoplakia. Clinical symptoms and treatment methods were described. The basic information sources were up to date articles. The author's results were retrospectively analysed.