Open AccessTHE ESTIMATION OF HYDROPHOBICITY AND THE ANALYSIS OF HYDROGEN BONDS IN THE MOST PERSISTENT CONFORMERS OF MOLECULES OF SYNTHESIZED ADAMANTYL-CONTAINING TRIPEPTIDES
Author(s) -
С.В. Обухов,
П. П. Пурыгин,
Е.А. Степанов,
Yu. P. Zarubin
Publication year - 2012
Publication title -
vestnik samarskogo universiteta. estestvennonaučnaâ seriâ
Language(s) - English
Resource type - Journals
eISSN - 2712-8954
pISSN - 2541-7525
DOI - 10.18287/2541-7525-2012-18-3.1-156-163
Subject(s) - tripeptide , conformational isomerism , hydrogen bond , intramolecular force , molecule , chemistry , computational chemistry , stereochemistry , organic chemistry , peptide , biochemistry
Adamantyl-containing tripeptides with potential antiviral activity are synthesized. Applying methods of computational chemistry hydrophobic properties were estimated. Search of the most persistent conformers was made and the analysis of intramolecular hydrogen bonds to these peptides was performed.