
Enhanced CNN Model for Pancreatic Ductal Adenocarcinoma Classification Based on Proteomic Data
Author(s) -
Kadiyala Laxminarayanamma,
Ravilla Venkata Krishnaiah,
P. Sammulal
Publication year - 2022
Publication title -
ingénierie des systèmes d'information/ingénierie des systèmes d'information
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.161
H-Index - 8
eISSN - 2116-7125
pISSN - 1633-1311
DOI - 10.18280/isi.270115
Subject(s) - pancreatic cancer , pancreatic ductal adenocarcinoma , computer science , profiling (computer programming) , convolutional neural network , proteomics , deep learning , artificial intelligence , cancer , bioinformatics , medicine , biology , biochemistry , gene , operating system
Pancreatic ductal adenocarcinoma (PDAC) is one of the deadliest tumors, with just around nine percent of those diagnosed surviving for more than five years after diagnosis. A significant part of the poor result may be attributed to late detection. However, the illness is identified at an initial phase. While growths remain quite tiny and manageable, five-year existence rates can rise to as high as seventy percent. Because of this, there is a huge clinical demand for the creation of a non-invasive examination targeted at the earliest identification of PDAC, which has the ability to recover the current prospects of patients. Considering the grim future for pancreatic cancer, new strategies for early detection and prevention must be developed as rapidly as feasible. Researchers have revealed that proteomics technology is effective in discovering important biomarkers for early-stage pancreatic cancer, according to recent research. One of the most challenging difficulties is recognizing and collecting physiologically relevant information from the huge quantity of data collected when it comes to proteome profiling. Because of the tremendous complexity of proteomics datasets and the fact that they typically have minuscule sample numbers, it is vital to apply non-classical statistical approaches for data processing. Deep learning models are more effective; few efforts have lately made to identify PDAC, but the models are not developed successfully. This paper used an enhanced Convolution neural network (CNN) model to classify pancreatic decease at different stages accurately to clinical correction. The model has effective results compared to existing models.