Open AccessA modified laser-induced choroidal neovascularization animal model with intravitreal oxidized low-density lipoprotein
Author(s) -
Tong Wu,
Kuan-Rong Dang,
YaFen Wang,
Bao-Zhen Lyu,
W. Xu,
GuoRui Dou,
Jian Zhou,
Yan-Nian Hui,
Hongjun Du
Publication year - 2020
Publication title -
international journal of ophthalmology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.634
H-Index - 29
eISSN - 2227-4898
pISSN - 2222-3959
DOI - 10.18240/ijo.2020.08.03
Subject(s) - medicine , choroidal neovascularization , ophthalmology , neovascularization , laser , low density lipoprotein , macular degeneration , angiogenesis , cholesterol , optics , physics
To investigate whether intravitreal injection of oxidized low-density lipoprotein (OxLDL) can promote laser-induced choroidal neovascularization (CNV) formation in mice and the mechanism involved, thereby to develop a better animal model.