Open AccessSensitized heat shock protein 27 induces retinal ganglion cells apoptosis in rat glaucoma model
Author(s) -
Wei Zhao,
Le Dai,
Xiaoting Xi,
Qian-Bo Chen,
Meixia An,
Yan Li
Publication year - 2020
Publication title -
international journal of ophthalmology
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 0.634
H-Index - 29
eISSN - 2227-4898
pISSN - 2222-3959
DOI - 10.18240/ijo.2020.04.01
Subject(s) - medicine , hsp27 , glaucoma , ophthalmology , retinal , retinal ganglion cell , apoptosis , intraocular pressure , intraperitoneal injection , tunel assay , ocular hypertension , heat shock protein , endocrinology , pathology , hsp70 , immunohistochemistry , chemistry , biochemistry , gene
To investigate the relationships between the changes of heat shock protein 27 antibody (anti-HSP27) in serum/cerebrospinal fluid (CSF), intraocular pressure (IOP), retinal ganglion cell (RGC) apoptosis in a rat glaucoma model and disclose the underlying pathogenesis of glaucoma.