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Osteosarcoma presenting as ludwig’s angina in a down’s syndrome patient: A case report
Author(s) -
Bhargav Ram,
Dhaya Ann Varghese,
Rishikesh Kumar,
Anuradha Naganagoudar,
Manjunath Vijapur,
Vasanth Kattimani
Publication year - 2021
Publication title -
journal of dental specialities/journal of dental specialties
Language(s) - English
Resource type - Journals
eISSN - 2393-9834
pISSN - 2320-7302
DOI - 10.18231/j.jds.2021.018
Subject(s) - osteosarcoma , medicine , retinoblastoma , down syndrome , angina , presentation (obstetrics) , radiation therapy , pediatrics , surgery , pathology , myocardial infarction , biochemistry , chemistry , psychiatry , gene
Individuals with Down's Syndrome are predisposed to leukaemia, possibly other malignancies, various infection as well as increased mortality from other causes. osteosarcoma has been linked to genetic illnesses such as hereditary retinoblastoma, Li-Fraumeni syndrome, and Rothman-Thomson syndrome, it has not been linked to Down syndrome. Treatment plan for osteosarcoma includes surgical resection with systemic chemotherapy. Osteosarcoma is highly resistant to radiotherapy. Here we present a 21 year old female patient which is a unique case of Osteosarcoma in Down’s Syndrome patient presenting as Ludwig’s Angina. This current report highlights a clinical presentation of Osteosarcoma in Down’s Syndrome.

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