Open AccessPrimary testicular T cell Non Hodgkin Lymphoma with unusual histomorphology: A rare case
Author(s) -
Nisarga Rani R,
K Madan,
Siddhartha Sankar Biswas,
Anjali Rao
Publication year - 2022
Publication title -
ip journal of diagnostic pathology and oncology/ip journal of diagnostic pathology and oncology/journal of diagnostic pathology and oncology
Language(s) - English
Resource type - Journals
eISSN - 2581-3706
pISSN - 2456-6284
DOI - 10.18231/j.jdpo.2022.012
Subject(s) - pathology , lymphoma , immunohistochemistry , parenchyma , medicine , orchiectomy
Primary testicular non-Hodgkin lymphoma (NHL) is an uncommon extra nodal lymphoma presentation, constituting 1-2% of all lymphomas. Majority are of B-Cell type, with very few cases being primary T-Cell phenotype. A 28 years male presented with painless, unilateral testicular swelling with elevated serum LDH levels, beta HCG and AFP serum levels were within normal limits. Gross evaluation of high inguinal orchidectomy specimen showed an enlarged homogenous, grey white lobulated mass with adjacent entrapped testicular parenchyma. Microscopy showed diffuse sheets of medium sized, monomorphic atypical lymphoid cells with sparing of adjacent seminiferous tubules. A panel of Immunohistochemistry markers done were suggestive of T-Cell Non-Hodgkin Lymphoma. Testicular T cell NHL are extremely rare amongst the testicular lymphomas, constituting for 5% of all testicular tumours. This case is being presented for its rarity in literature, especially in young age group and the unusual histomorphology.