Open AccessA case report on long segment hirschprung’s disease
Author(s) -
D Suganya,
Raja Kannan,
Anjali Priya,
K. Arun Chander Yadav
Publication year - 2021
Publication title -
indian journal of pharmacy and pharmacology
Language(s) - English
Resource type - Journals
eISSN - 2393-9087
pISSN - 2393-9079
DOI - 10.18231/j.ijpp.2021.041
Subject(s) - disease , hirschsprung's disease , medicine , phenotype , enteric nervous system , genetic syndromes , genetic disorder , pediatrics , bioinformatics , biology , genetics , gene
Hirschsprung disease is a complex congenital condition of the intestine, usually recognized to be genetic origin and reverberates from a disturbance of the normal development of the enteric nervous system. It is evident to be the most common cause of a low intestinal obstruction in the neonates as well as the older children. Study reveals that occurrence rate of cases in 70% may be associated with other congenital abnormalities together with number of syndromic phenotypes. A number of distinct genetic sites have been identified in these syndromic phenotypes, identifying potential genetic predispositions. Presenting hereby a case of neonatal hirschsprung’s disease whereby the patient was surgically corrected along with stepwise pharmacological therapy and was able to get discharged with regular follow up advice.