
Formulation and evaluation of herbal gel for management of mouth ulcers
Author(s) -
Kanchan Upadhye,
kirti Charde,
Gauri Dixit,
Suparna Bakhle
Publication year - 2021
Publication title -
indian journal of pharmacy and pharmacology
Language(s) - English
Resource type - Journals
eISSN - 2393-9087
pISSN - 2393-9079
DOI - 10.18231/j.ijpp.2021.039
Subject(s) - antimicrobial , traditional medicine , medicine , food science , chemistry , microbiology and biotechnology , biology
: or mouth ulcers is the most common condition that we encounter. Clinically the lesions are single or multiple superficial and deep sealed and are associated with microbial invasions. : This study was conducted with the aim of evaluating the effectiveness of herbal drugs for treatment of In the research work, mouth ulcer gels were formulated incorporating the extracts of as and using 934 as the gelling agent. Seven batches were formulated by varying the concentration of the herbal ingredients (F1 to F7)The prepared formulations were evaluated for various parameters like physical appearance, pH, Homogeneity and antimicrobial activity against fungi and bacteria. The antimicrobial activity was also compared with a marketed gel formulation. All the prepared formulation using different concentration of plant extract showed the pH values in between 6.1±0.2 to 7.0±0.1. The values ranged between the 5.0 to 8.0 cm. Out of all the formulations, formulation F7 containing all the three herbal extracts showed a goodand very promising antimicrobial activity comparable with a marketed gel. Thus stable, effective gels containing herbal ingredients for management of mouth ulcers can be developed.