Open AccessD Dimer – Prognostic indicator for disease severity in patients hospitalised with COVID 19
Author(s) -
Vineet Banga,
Stuti Jain
Publication year - 2021
Publication title -
indian journal of pathology and oncology
Language(s) - English
Resource type - Journals
eISSN - 2394-6792
pISSN - 2394-6784
DOI - 10.18231/j.ijpo.2021.096
Subject(s) - d dimer , medicine , covid-19 , biomarker , severity of illness , disease , retrospective cohort study , gastroenterology , infectious disease (medical specialty) , biochemistry , chemistry
Patients of Covid 19 infections present with different severity. Levels of D Dimer in these patients can be correlated with disease severity for management and prognosis. To evaluate the usefulness of D-Dimer levels in blood to correlate with disease severity in COVID 19 patients. Retrospective study was done in Department of Pathology of Secondary Care hospital that became designated covid hospital from May 2021 to June 2021 on 60 COVID 19 positive admitted patients. D dimer levels were analysed and correlated with clinical severity of disease. Out of total 60 patients, 33 were in mild, 23 in moderate and 4 were in severe category. In mild cases D Dimer varies from 43 ng/ml to 183 ng/ml. In moderate cases D Dimer varies from 270 ng/ml to 991 ng/ml. In severe cases D Dimer varies from 1043 ng/ml to 2463 ng/ml. The study suggests cut off levels for D Dimer as up to 200 ng/ml for mild, 200-1000 ng/ml for moderate and more than 1000 ng/ml for severe category in COVID 19 patients. D dimer helps in identifying severe disease and can be used as an essential biomarker in developing the management protocol for COVID 19 patients.