Open AccessDetermination of potential sources of drug development for menstrual disorders: A qualitative analysis of published literature of in-vitro rat uterus experimental studies
Author(s) -
Paroma Arefin,
Shehan Habib,
Aishawarya Arefin,
Md Saidul Arefin
Publication year - 2021
Publication title -
international journal of pharmaceutical chemistry and analysis
Language(s) - English
Resource type - Journals
eISSN - 2394-2797
pISSN - 2394-2789
DOI - 10.18231/j.ijpca.2021.010
Subject(s) - uterus , contractility , medicine , drug , menstruation , adverse effect , traditional medicine , uterine contraction , pharmacology , menstrual cycle , medicinal plants , physiology , obstetrics , gynecology , hormone
Many herbal plants have been recorded in medicine for their usefulness in menstrual disorders, however, a few have been extensively examined for their pharmacological activities. These plants have been recorded to have usefulness in the management of painful menses, preventing miscarriages, prolonging birth, or inducing birth. Therefore, the effects of herbal plants on the contractility of the uterus will be investigated using the in-vitro experiment of the isolated rat uterus. The study aims to assess the most outstanding plants that are used to treat menstrual disorders, their uterine contractility properties, and adverse effects. The study will therefore acknowledge the importance of medicinal plants in the study of new drugs for regulating uterine contractility and propose suggestions for improving experiments involving medicinal plants on uterine contractility for drug development. The study will provide a direction as to whether the plant extract has drug development potential.