Open AccessOutfacing second wave of pandemic in COVID-19 positive mothers at Gandhi hospital
Author(s) -
Amreen Sharif,
Vellanki Janaki
Publication year - 2021
Publication title -
indian journal of obstetrics and gynecology research
Language(s) - English
Resource type - Journals
eISSN - 2394-2754
pISSN - 2394-2746
DOI - 10.18231/j.ijogr.2021.112
Subject(s) - medicine , pandemic , cytokine storm , pregnancy , covid-19 , coagulopathy , obstetrics and gynaecology , intensive care medicine , pediatrics , disease , infectious disease (medical specialty) , biology , genetics
The novel coronavirus is a single stranded RNA virus with spike proteins triggering an immune response leading to cytokine storm and coagulopathy. Pregnancy is an immunocompromised and hypercoagulable state, with predisposition to severe illness. An insight into impact of COVID-19 in pregnancy is essential to combat its future. This study was conducted at a tertiary care centre. Analytical study was conducted from the data collected regarding COVID-19 positive labour room admissions, deliveries and deaths during the second wave of pandemic. There was a discharge rate of 88.14% after safe delivery. Among COVID-19 maternal mortalities, most deaths were due to ARDS. Quick SOFA score was a good predictor for morbidity and mortality. Deranged coagulation profile and D-Dimer levels more than 500 ng/ml were good predictors of mortality. Silent hypoxia needs to be identified and corrected at admission. Delay in seeking medical advice was a major contributory risk factor. Increasingawareness among public about seeking medical advice during early stages of disease. Early identification and treatment according to latest guidelines for a positive outcome.Making aware the policy makers regarding risk-benefits of vaccination in mothers can come a long way in changing the fate of COVID-19 in pregnancy.