Open AccessIncreased first trimester serum uric acid as a predictor of Gestational diabetes mellitus
Author(s) -
Irkm Sivasarupa,
Ushadevi Gopalan,
Sivankumar Kumarapillai
Publication year - 2021
Publication title -
indian journal of obstetrics and gynecology research
Language(s) - English
Resource type - Journals
eISSN - 2394-2754
pISSN - 2394-2746
DOI - 10.18231/j.ijogr.2021.063
Subject(s) - medicine , gestational diabetes , pregnancy , hyperuricemia , uric acid , body mass index , obstetrics , diabetes mellitus , gestation , gestational age , endocrinology , genetics , biology
Women with raised uric acid in pregnancy are interlinked with more incidence of unfavourable outcomes in pregnancy such as gestational diabetes mellitus. The study aims at testing the hypothesis that elevated uric acid in first trimester of pregnancy is associated with subsequent development of gestational diabetes. : All pregnant women less than 12 weeks were included in this study after informed consent. Blood samples were collected for serum uric acid analysis and all these patients were followed up with oral glucose tolerance test at twenty-four to twenty-eight weeks of gestation. The mean age of pregnant women was 29.84 ± 4.94 years. The mean height and weight was 151.52 ± 7.49 cms and 50.60 ± 6.88 kg respectively. The body mass index of patients was 22.13 ± 3.31 kg/m.The mean gestational age of pregnant women was 11.14 ± 1.30 weeks. The mean uric acid level was 3.81 ± 1.24 mg/dl. In this study the p value was 0.018 using chi-square test which was significant. Hyperuricemia in first trimester is a reliable marker for the prediction of gestational diabetes mellitus in later pregnancy.