Open AccessA review: Management of motor neuron diseases
Author(s) -
Aarti Chopra,
Ravi Kumar,
Girendra Kumar Gautam
Publication year - 2022
Publication title -
ip indian journal of neurosciences/ip indian journal of neurosciences
Language(s) - English
Resource type - Journals
eISSN - 2581-916X
pISSN - 2581-8236
DOI - 10.18231/j.ijn.2021.053
Subject(s) - amyotrophic lateral sclerosis , motor neuron , neuroscience , upper motor neuron , lower motor neuron , motor system , disease , medicine , physical medicine and rehabilitation , psychology , pathology
Motor neuron diseases are a group of chronic sporadic and hereditary neurological disorders characterized by progressive degeneration of motor neurons. These might affect the upper motor neurons, lower motor neurons, or both. The prognosis of the motor neuron disease depends upon the age at onset and the area of the central nervous system affected. Amyotrophic lateral sclerosis (ALS) has been documented to be fatal within three years of onset. This activity focuses on amyotrophic lateral sclerosis as the prototype of MND, which affects both the upper and the lower motor neurons and discusses the role of inter-professional team in the differential diagnosis, evaluation, treatment, and prognostication. It also discusses various other phenotypes of MND with an emphasis on their distinguishing features in requisite detail.